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Synthesis of [1-11C]D-glucosamine and evaluation of its in vivo distribution in rat with PET

✍ Scribed by Jan-Olov Thorell; Sharon Stone-Elander; Hans von Holst; Martin Ingvar

Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
723 KB
Volume
44
Category
Article
ISSN
0969-8043

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✍ Jan-Olov Thorell; Sharon Stone-Elander; Martin Ingvar; Lars Eriksson 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 403 KB

## Abstract A method for labelling 6,7‐dichloro‐2,3‐dihydroxyquinoxaline (DCQX) in position 2 with carbon‐11 is presented. Diethyl [1‐^11^C]oxalate was synthesized in a two‐step, microwave‐assisted procedure from no‐carrier‐added [^11^C]cyanide and was reacted with 4,5‐dichloro‐1,2‐phenylenediamine