Synthesis, NMR spectroscopic and X-ray crystallographic studies of functionalized 2-aminopyrrolin-4-ones
✍ Scribed by Anna Gola; Evangelia Samartzi; Vassilios Bardakos; Margarita Petroliagi; Olga Igglessi-Markopoulou; John Markopoulos; James V. Barkley
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2000
- Tongue
- English
- Weight
- 305 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
Abstract
An efficient method for the preparation of novel cyano derivatives of 4‐amino‐3‐hydroxybutenoic acids 4–8 and N‐substituted‐2‐aminopyrrolin‐4‐ones 9–18 is described; the structure of compound 13 has been elucidated with X‐ray analysis.
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2,4-Dinitrodiphenylamine (DNDPA) has been studied as regards its crystal structure and thermal decomposition characteristics using Xray diffraction (XRD), simultaneous thermal analysis, ultraviolet and visible spectroscopy, infrared spectroscopy, hot-stage microscopy and high performance liquid chro
## Abstract An efficient method for the preparation of optically active derivatives of γ‐amino‐butenoic acids and their cyclic derivatives, 2‐amino‐pyrrolin‐4‐ones, from α‐amino acids is described. Partial racemization accompanies the formation of initial unsaturated γ‐amino‐β‐hydroxy esters **5–8*