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Synthesis, molecular modeling, and biological evaluation of cinnamic acid metronidazole ester derivatives as novel anticancer agents

โœ Scribed by Yong Qian; Hong-Jia Zhang; Hao Zhang; Chen Xu; Jing Zhao; Hai-Liang Zhu


Book ID
108072863
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
451 KB
Volume
18
Category
Article
ISSN
0968-0896

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## Abstract Synthesis and evaluation of the antimicrobial and cytotoxic activity of two series of polysubstituted pyrimidines comprising the thioether functionality and other pharmacophores, reported to contribute to various chemotherapeutic activities are described. All newly synthesized compounds