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Synthesis, in vitro binding and biodistribution in B16 melanoma-bearing mice of new iodine-125 spermidine benzamide derivatives

✍ Scribed by Marie-France Moreau; Janine Papon; Pierre Labarre; Nicole Moins; Michèle Borel; Martine Bayle; Bernadette Bouchon; Jean-Claude Madelmont


Book ID
116798859
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
187 KB
Volume
32
Category
Article
ISSN
0969-8051

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## Abstract 7‐(CH~3~)~3~N‐4‐{2,4‐(NO~2~)~2~C~6~H~3~S}‐nido‐7‐CB~10~H~11~ has been synthesized through a Friedel‐Crafts substitution reaction on 7‐(CH~3~)3N‐__nido__‐7‐ CB~10~H~12~. A biodistribution study in mice with implanted B16 melanoma indicates that the compound locates in neoplastic tissue a