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Synthesis, in vitro and in vivo evaluation of [11C]-methyl-BIII277CL as a pet radioligand for imaging the pcp-binding site of the NMDA-receptor complex

✍ Scribed by M. Kokic; S. Ametamey; M. Honer; L. Kessler; M. Grauert; P. A. Schubiger

Book ID: 112132562
Publisher: John Wiley and Sons
Year: 2001
Tongue: French
Weight: 156 KB
Volume: 44
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580440112

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## Abstract Carbon‐11 labelled befloxatone ((5R)‐5‐(methoxymethyl)‐3‐[4‐[(3R)‐4,4,4‐trifluoro‐3‐hydroxybutoxy]phenyl]‐2‐oxazolidinone) is a reversible and selective monoamine oxidase‐A (MAO‐A) inhibitor and appears to be a new potent PET tracer for the __in vivo__ imaging of MAO‐A density. In this