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Synthesis in the emetine series—XIV : A new synthesis of 2,3,11-trisubstituted berbines

✍ Scribed by A. Brossi; H. Bruderer; A.I. Rachlin; S. Teitel


Book ID
103398500
Publisher
Elsevier Science
Year
1968
Tongue
French
Weight
669 KB
Volume
24
Category
Article
ISSN
0040-4020

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## Abstract 1‐Substituted‐3‐dimethylaminopropenones **1a‐d** reacted with acetylacetone and with ethyl acetoacetate to yield regioselectively 2,3,6‐trisubstituted pyridines. Refluxing **1a‐d** in acetic acid/ammonium acetate resulted in the formation of 6‐substituted‐3‐aroylpyridines, whereas reflu