Synthetic studies of pseudolaric acid B, 2, provided a relay synthesis of pseudolaric acid B (PLAB) via aldehyde 5. The aldehyde 5 can serve: to complete the total synthesis of PLAB; as a precursor for the synthesis of PLAB analogs; or as a substrate for the generation of radiolabeled PLAB for mecha
โฆ LIBER โฆ
Synthesis in the diterpene alkaloid series - I the stereospecific synthesis of an intermediate and its identification with a natural degradation product
โ Scribed by J.A. Findlay; W.A. Henry; T.C. Jain; Z. Valenta; K. Wiesner; C.M. Wong
- Publisher
- Elsevier Science
- Year
- 1962
- Tongue
- French
- Weight
- 184 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0040-4039
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The cinchona alkaloid-mediated opening of prochiral cyclic anhydrides in the presence of benzyl alcohol leading to optically active hemiesters is described. Structurally diverse anhydrides are converted into their corresponding benzyl monoesters with either enantiomer being obtained with up to 99% e