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Synthesis in solution of peptoids using fmoc-protected n-substituted glycines

✍ Scribed by John A.W. Kruijtzer; Rob M.J. Liskamp


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
237 KB
Volume
36
Category
Article
ISSN
0040-4039

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A particularly interesting class of oligomeric peptidomimetics is formed by the peptoids, which consist of N-substituted glycine residues. A solidphase synthesis method for peptoids is presented in which these residues are introduced using their Fmoc derivatives. This ΒͺmonomerΒΊ method allowed the mo