## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Simultaneous Use of N-Fmoc and OTmse Protective Groups in the Synthesis of Peptolytic Sensitive Peptides
β Scribed by L. Vanfleteren; M. J. O. Anteunis
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Weight
- 828 KB
- Volume
- 97
- Category
- Article
- ISSN
- 0037-9646
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π SIMILAR VOLUMES
Amino acid derivatives protected at the a-or side chain amino function with mono-as well as dimethoxytrityl were successfully prepared by a one-step procedure. These derivatives were evaluated for their utilization in solid phase peptide synthesis (SPPS), particularly with respect to the selective d
In this communication we introduce a promising masking agent --the vinyloxycarbonyl or VOC group --for the protection of amino functions in peptide chemistry. Amino acids are easily converted to their N-VOC derivatives (l\_) in dilute aqueous base using the known vinyl chloroformate' in dioxane as t
We wish to report our first studies on the possibility of applying the acetoacetyl group CHzCOCHzCC-(AA), to the protection of amino groups in peptide synthesis.