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Synthesis, DNA Binding and Antiviral Activity of New Uracil, Xanthine, and Pteridine Derivatives

✍ Scribed by Osama I. El-Sabbagh; Mohamed E. El-Sadek; Samar El-Kalyoubi; Ibrahim Ismail


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
684 KB
Volume
340
Category
Article
ISSN
0365-6233

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Synthesis and antiviral activity of new
✍ Annalisa Tait; Amedeo Luppi; Claudio Cermelli πŸ“‚ Article πŸ“… 2004 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 187 KB πŸ‘ 1 views

## Abstract A series of 2,1,3‐ and 1,2,4‐benzothiadiazine derivatives were synthesized by alkylation __via__ Mitsunobu reaction and evaluated for their antiviral activity against ADV, HHV‐6, Cox‐B5 and H‐CMV. Most of them were active at micromolar level against one or more viral strains. All the mo