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Synthesis, Conformational Analysis, and Evaluation of the Multidrug Resistance-Reversing Activity of the Triamide and Proline Analogs of Hapalosin

โœ Scribed by Dinh, Tam Q.; Du, Xiaohui; Smith, Charles D.; Armstrong, Robert W.


Book ID
126211441
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
293 KB
Volume
62
Category
Article
ISSN
0022-3263

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ChemInform Abstract: Synthesis and Confo
โœ T. Q. DINH; X. DU; R. W. ARMSTRONG ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 40 KB ๐Ÿ‘ 2 views

Synthesis and Conformational Analysis of the Multidrug Resistance-Reversing Agent Hapalosin (XIIIa) and Its Non-N-methyl Analogue (XIIIb) . -The key steps in the synthesis of (XIIIa) include two Brown allylboration reactions to obtain the chiral precursors (II) and (V) and macrolactonization of the