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Synthesis, characterization, antifungal, antibacterial, and antitumor activities of some tris(pentafluorophenyl)arsenic(V) derivatives

✍ Scribed by Rahul Mishra; Kiran Singhal; Ashok Ranjan; A. K. Saxena; Prem Raj

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
126 KB
Volume
21
Category
Article
ISSN
1042-7163

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✦ Synopsis

A series of tris(pentafluorophenyl) arsenic(V) derivatives of the type (C 6 F 5 ) 3 AsL 2 , (C 6 F 5 ) 3 As(Cl)(L) [L = OCOC 6 H 4 (o-OH), OCOC-(OH)(C 6 H 5 ) 2 , and 2-(6-OCH 3 C 10 H 6 )CH(CH 3 ) COO ], and cycloarsenates, O C(O) (C 6 F 5 ) 3 As O

CHR (R = C 6 H 5 , p-CF 3 C 6 H 4 , and p-OCH 3 C 6 H 4 ) have been isolated and characterized by elemental analysis and spectroscopic data (infrared; 1 H, 19 F, and 13 C NMR). These compounds were screened for their in vitro antifungal, antibacterial, and antitumor activities and were found to show moderate to significant activity.

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.