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Synthesis, characterization, and SAR studies of new (1H-indol-3-yl)alkyl-3-(1H-indol-3-yl)propanamide derivatives as possible antimicrobial and antitubercular agents

✍ Scribed by Ranjith Pakkath Karuvalam, Rajeesh Pakkath…


Book ID
120908690
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
783 KB
Volume
22
Category
Article
ISSN
1054-2523

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✍ Vijai N. Pathak; Ragini Gupta; Meenu Garg 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 120 KB 👁 2 views

## Abstract Ketene generated from acetyl chloride or chloroacetyl chloride adds on indolyl Schiff's base double bond to afford 1‐butyl‐3‐substituted‐4‐(2‐aryl‐1__H__‐indol‐3‐yl)‐2‐azetidinones in THF. The reaction proceeds stereospecifically via concerted __trans__ [2+2] cycloaddition. The synthesi