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Synthesis, Characterization, and Relaxivity of Two Linear Gd(DTPA)−Polymer Conjugates

✍ Scribed by Duarte, M. G.; Gil, M. H.; Peters, J. A.; Colet, J. M.; Elst, L. Vander; Muller, R. N.; Geraldes, C. F. G. C.

Book ID
120791682
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
101 KB
Volume
12
Category
Article
ISSN
1043-1802

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## Abstract A series of linear copolymers of DTPA‐class Gd^3+^ conjugates, linked by α,ω‐alkyldiamides with a varying number (__n__) of methylenes separating the amide function, were synthesized. Surprisingly, their relaxivities at all fields increased with increasing __n__. At MRI fields and 35°C,