Synthesis, Characterization and Photocytotoxicity of a Glycoconjugated meso-Monoarylbenzochlorin. -The title compound (I) is prepared efficiently from meso monoaryl porphyrin and 3-(dimethylamino)acrolein by a regiospecific Vilsmeier reaction followed by cyclization and glycosylation. It shows good
โฆ LIBER โฆ
Synthesis, characterization and photocytotoxicity of a glycoconjugated meso-monoarylbenzochlorin
โ Scribed by Philippe Maillard; Clotilde Hery; Michel Momenteau
- Book ID
- 104257073
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 260 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
Amphiphilic glycoconjugated benzochlorin was prepared efficiently from meso monoaryl porphyrin and 3-(dimethylamino)acrolein by regiospecific Vilsmeier's reaction followed by cyclisation under acidic conditions and glycosylation, This compound displays a good in vitro photocytotoxicity on tumor cell lines after irradiation with light > 590 nm.
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