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ChemInform Abstract: Synthesis, Characterization and Photocytotoxicity of a Glycoconjugated meso-Monoarylbenzochlorin.

✍ Scribed by P. MAILLARD; C. HERY; M. MOMENTEAU


Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis


Synthesis, Characterization and Photocytotoxicity of a Glycoconjugated meso-Monoarylbenzochlorin.

-The title compound (I) is prepared efficiently from meso monoaryl porphyrin and 3-(dimethylamino)acrolein by a regiospecific Vilsmeier reaction followed by cyclization and glycosylation. It shows good phototoxicity in vitro on HT 29 tumor cells after irradiation with


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