ChemInform Abstract: Synthesis and Phototoxic Property of Tetra- and Octa-Glycoconjugated Tetraphenylchlorins.
โ Scribed by Yuji Mikata; Yoko Onchi; Minako Shibata; Toyoji Kakuchi; Hiroshi Ono; Shun-ichiro Ogura; Ichiro Okura; Shigenobu Yano
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 27 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
โฆ Synopsis
Synthesis and Phototoxic Property of Tetra-and Octa-Glycoconjugated Tetraphenylchlorins.
-The title compounds such as (I) are prepared via a diimine reduction of the peracetylated sugar porphyrin derivatives with subsequent deprotection. The physicochemical properties of these compounds are examined and the usefulness for a photodynamic therapy is discussed.
๐ SIMILAR VOLUMES
Synthesis, Characterization and Photocytotoxicity of a Glycoconjugated meso-Monoarylbenzochlorin. -The title compound (I) is prepared efficiently from meso monoaryl porphyrin and 3-(dimethylamino)acrolein by a regiospecific Vilsmeier reaction followed by cyclization and glycosylation. It shows good