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Synthesis, characterization, and in vitro antitumor activity of some tin(IV)–oxygen and tin(IV)–sulfur heterocycles

✍ Scribed by Mohammed Bouâlam; Rudolph Willem; Monique Biesemans; Bernard Mahieu; Marcel Gielen

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
524 KB
Volume
2
Category
Article
ISSN
1042-7163

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✦ Synopsis

Abstract

The synthesis of diorganotin(IV) derivatives of thiosalicylic acid, of 3‐aza‐2‐thiosalicylic acid, and of several related compounds is reported. Their characterization by ^1^H, ^13^C, and ^119^Sn NMR, Mössbauer, and mass spectrometry is described. The in vitro antitumor activity of selected derivatives against two human tumoral cell lines is discussed.

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