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Synthesis, characterization and in-vitro anti-inflammatory activity of some substituted 1,2,3,4 tetrahydropyrimidine derivatives

✍ Scribed by Gondkar, Anita S.; Deshmukh, Vinayak K.; Chaudhari, Sanjay R.

Book ID
122209214
Publisher
Elsevier
Year
2013
Tongue
English
Weight
416 KB
Volume
5
Category
Article
ISSN
0975-7619

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Synthesis and anti-inflammatory activity
Synthesis and anti-inflammatory activity of some 3-(4,6-disubtituted-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl) propanoic acid derivatives
✍ Santosh N. Mokale; Sandeep S. Shinde; Rupali D. Elgire; Jaiprakash N. Sangshetti πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 751 KB

A series of 3-(4,6-disubtituted-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl) propanoic acid derivatives has been synthesized by condensation of thiourea, 5-(4-subtituted phenyl)-5-oxopentanoic acid and substituted aldehyde. The synthesized compounds were screened for their anti-inflammatory activity u