Synthesis and Muscarinic Activity of 1,2,3,4-Tetrahydropyrimidine Derivatives
✍ Scribed by Myung Hee Jung; Jewn-Giew Park; Kong Jae Yang; Mi-Jeoung Lee
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 123 KB
- Volume
- 334
- Category
- Article
- ISSN
- 0365-6233
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract A one‐pot synthesis of __N__‐sulfonyl‐2‐alkylidene‐1,2,3,4‐tetrahydropyrimidines __via__ a highly selective and copper‐catalyzed multicomponent reaction of sulfonyl azides, terminal alkynes and α,β‐unsaturated imines has been developed. The α,β‐unsaturated imine substrates could be gene
Arecoline and other arecaidine esters are semirigid derivatives of the reverse carboxy-analogue of acetylcholine with high muscarinic potencies and intrinsic activities'). Among the arecaidine esters the propargyl derivative 1 is more potent than arecoline and even acetylcholine'). Since the bioisos