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Synthesis, characterization and crystal structures of two 2-naphthyl substituted pyrazoles

✍ Scribed by Guang Yang; Raphael G. Raptis


Publisher
Journal of Heterocyclic Chemistry
Year
2003
Tongue
English
Weight
74 KB
Volume
40
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

The synthesis, characterization and X‐ray crystal structures of two 2‐naphthyl‐substituted pyrazoles ‐ 3‐(2‐naphthyl) pyrazole (1) and 5‐(2‐naphthyl)‐3‐trifluoromethyl‐pyrazole (3) ‐ are reported. In addition, the isolation and structural characterization of 5‐hydroxy‐3‐(2‐naphthyl)‐5‐trifluoromethyl‐4,5‐dihydropyrazole (2), an intermediate of the synthesis of 3, is included. Two simple methods of dehydration of 2 are also presented.


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