Synthesis of oligonucleotide derivatives
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Kazushige Yamana; Mizuki Takei; Hidehiko Nakano
📂
Article
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1997
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Elsevier Science
🌐
French
⚖ 248 KB
The synthesis of a pyrene labeled glycerol linker for multiple internal labeling of oligonucleolides has been described. The ofigonucleotide containing two successively incorporated pyrenyl residues exhibits enhanced excimer fluorescence upon hybridization to the complements~ DNA segment.