✦ LIBER ✦
Synthesis of oligonucleotide derivatives containing pyrene labeled glycerol linkers: Enhhanced excimer fluorescence on binding to a complementary DNA sequence
✍ Scribed by Kazushige Yamana; Mizuki Takei; Hidehiko Nakano
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 248 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
The synthesis of a pyrene labeled glycerol linker for multiple internal labeling of oligonucleolides has been described. The ofigonucleotide containing two successively incorporated pyrenyl residues exhibits enhanced excimer fluorescence upon hybridization to the complements~ DNA segment.