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Synthesis, antiproliferative activity, acute toxicity and assessment of the antiandrogenic activities of new androstane derivatives

✍ Scribed by Neelima Dhingra; T. R. Bhardwaj; Neeraj Mehta; Tapas Mukhopadhyay; Ashok Kumar; Manoj Kumar

Book ID
107642499
Publisher
Springer
Year
2011
Tongue
English
Weight
643 KB
Volume
34
Category
Article
ISSN
0253-6269

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## Abstract Ten pyrrole derivatives (including six new compounds) were synthesized and evaluated as potential platform for analgesic agents' development. Acute intraperitoneal toxicity and analgesic activity studies (acetic acid writhing test) were performed on mice with acetylsalicylic acid used a