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Synthesis, Acute Toxicity, and Analgesic Activity of New Derivatives of Pyrrole.

✍ Scribed by Nikolai Danchev; Atanas Bijev; Diana Yaneva; Stanislava Vladimirova; Irina Nikolova

Publisher
John Wiley and Sons
Year
2007
Weight
23 KB
Volume
38
Category
Article
ISSN
0931-7597

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Synthesis, Acute Toxicity, and Analgesic
Synthesis, Acute Toxicity, and Analgesic Activity of New Derivatives of Pyrrole
✍ Nikolai Danchev; Atanas Bijev; Diana Yaneva; Stanislava Vladimirova; Irina Nikol πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 479 KB πŸ‘ 2 views

## Abstract Ten pyrrole derivatives (including six new compounds) were synthesized and evaluated as potential platform for analgesic agents' development. Acute intraperitoneal toxicity and analgesic activity studies (acetic acid writhing test) were performed on mice with acetylsalicylic acid used a