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Synthesis, antimicrobial, anticancer, antiviral evaluation and QSAR studies of 4-(1-aryl-2-oxo-1,2-dihydro-indol-3-ylideneamino)-N-substituted benzene sulfonamides

✍ Scribed by Kumar, Mahesh; Ramasamy, Kalavathy; Mani, Vasudevan; Mishra, Rakesh Kumar; Majeed, Abu Bakar Abdul; Clercq, Erik De; Narasimhan, Balasubramanian


Book ID
120296291
Publisher
Elsevier
Year
2014
Tongue
English
Weight
599 KB
Volume
7
Category
Article
ISSN
1878-5352

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✍ Vijai N. Pathak; Ragini Gupta; Meenu Garg πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 120 KB πŸ‘ 2 views

## Abstract Ketene generated from acetyl chloride or chloroacetyl chloride adds on indolyl Schiff's base double bond to afford 1‐butyl‐3‐substituted‐4‐(2‐aryl‐1__H__‐indol‐3‐yl)‐2‐azetidinones in THF. The reaction proceeds stereospecifically via concerted __trans__ [2+2] cycloaddition. The synthesi