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Synthesis, antimicrobial and cytotoxic activities of sulfone linked bis heterocycles

✍ Scribed by Muralikrishna, A.; Venkatesh, B.C.; Padmavathi, V.; Padmaja, A.; Kondaiah, P.; Krishna, N. Siva


Book ID
119234032
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
323 KB
Volume
54
Category
Article
ISSN
0223-5234

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Synthesis and antimicrobial activity of
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A new class of methyleneamine-linked bis-heterocycles that exhibit antimicrobial activity was synthesized. Bromination of 1 followed by condensation with thiourea gave 3. The reaction of 3 with propargyl bromide in dry toluene under inert atmosphere led to the formation of 4. Its subsequent reaction