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Synthesis and antimicrobial activity of amine linked bis- and tris-heterocycles

โœ Scribed by Bhanu Prakash, T.; Dinneswara Reddy, G.; Padmaja, A.; Padmavathi, V.


Book ID
124108359
Publisher
Elsevier Science
Year
2014
Tongue
French
Weight
345 KB
Volume
82
Category
Article
ISSN
0223-5234

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A new class of methyleneamine-linked bis-heterocycles that exhibit antimicrobial activity was synthesized. Bromination of 1 followed by condensation with thiourea gave 3. The reaction of 3 with propargyl bromide in dry toluene under inert atmosphere led to the formation of 4. Its subsequent reaction