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Synthesis, antimicrobial and antioxidant activities of 5-((2-oxo-2H-chromen-7-yloxy)methyl)-1,3,4-thiadiazol-2(3H)-one derived from umbelliferone

✍ Scribed by Al-Amiery, Ahmed A.; Al-Temimi, Ali A.; Sulaiman, Ghassan M.; Aday, Hamdan A.; Kadhum, Abdul Amir Hassan; Mohamad, Abu Bakar


Book ID
121301279
Publisher
Springer
Year
2013
Tongue
English
Weight
76 KB
Volume
48
Category
Article
ISSN
0009-3130

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## Abstract The key 3-(2-oxo-2H-chromen-3-yl)-2-oxo-2H,5H-pyrano[3,2-c]chromen-5-yl acetates 3 were synthesized in high yields by cyclocondensation of 4-oxo-4H-chromen-3-carbaldehydes 1 with coumarin-3-acetic acids 2 under mild conditions. The reaction pathway involves aldol condensation and subseq