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Synthesis, reactions and antineoplastic activity of 3-(2-oxo-2H-chromen-3-yl)-2-oxo-2H,5H-pyrano[3,2-c]chromene derivatives

✍ Scribed by Gašparová, Renata ;Koiš, Pavol ;Lácová, Margita ;Kováčová, Silvia ;Boháč, Andrej


Book ID
119990087
Publisher
Walter de Gruyter GmbH
Year
2013
Tongue
English
Weight
971 KB
Volume
11
Category
Article
ISSN
2391-5420

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Synthesis, reactions and antineoplastic
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## Abstract The key 3-(2-oxo-2H-chromen-3-yl)-2-oxo-2H,5H-pyrano[3,2-c]chromen-5-yl acetates 3 were synthesized in high yields by cyclocondensation of 4-oxo-4H-chromen-3-carbaldehydes 1 with coumarin-3-acetic acids 2 under mild conditions. The reaction pathway involves aldol condensation and subseq

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Single-crystal X-ray study T = 296 K Mean '(C±C) = 0.003 A Ê Disorder in main residue R factor = 0.040 wR factor = 0.101 Data-to-parameter ratio = 12.8 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.