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Synthesis, antimicrobial activity and binding properties of calix[4]arene based vancomycin mimics

✍ Scribed by Alessandro Casnati; Massimo Fabbi; Nicola Pelizzi; Andrea Pochini; Francesco Sansone; Rocco Unguro; Enza Di Modugno; Giorgio Tarzia

Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
309 KB
Volume
6
Category
Article
ISSN
0960-894X

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✦ Synopsis

Biologically active Vancomycin antibiotic mimics have been synthesized by linking two opposite aromatic nuclei of a calix[4]arene derivative in the cone conformation with a polifunctional bridge containing D-or L-alanine units and a diethylentriamine segment.

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