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Synthesis and X-ray structure of new spiro-imidazo[2,1-b]thiazole

✍ Scribed by Yaqing Feng; Weihong Zhang; Ligong Chen; J. Froelich; K. Meretter; F. Sauter

Publisher
Journal of Heterocyclic Chemistry
Year
1999
Tongue
English
Weight
301 KB
Volume
36
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

Spiro[5,5]undecane‐3‐one 1 was converted to 4,7‐dihydrospiro[benzo[d]thiazole‐6(5__H__),1′‐cyclohexane]‐2‐amine 3, which is condensed with bromomethyl (halo)phenyl ketones and cyclized to compounds 5a‐5c. The X‐ray crystallography of the 5b reveals that formation route for 5 is via 3‐position‐substituted‐spiro‐iminothiazole 4.

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ChemInform Abstract: Synthesis and X-Ray
ChemInform Abstract: Synthesis and X-Ray Structure of New Spiroimidazo[2,1-b]thiazole.
✍ Yaqing Feng; Weihong Zhang; Ligong Chen; J. Froelich; K. Meretter; F. Sauter 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views

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