Synthesis and X-ray Structure of a Shape-Persistent Macrocyclic Amphiphile
✍ Scribed by Dr. Sigurd Höger; Dr. Volker Enkelmann
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 439 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0044-8249
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📜 SIMILAR VOLUMES
The template-directed synthesis of shape-persistent macrocyclic amphiphiles is described. Two macrocycles with convergently arranged functional groups (hydroxyl and carboxylic acids) are prepared by intramolecular Glaser coupling of the appropriate templated tetraacetylenes. These structures are for
tetrathiacyclooctadecane (3) have been obtained by intermolecular cyclization of 1,3-bis(2-bromoethyl)adamantane (4) with thioacetamide using a high-dilution technique. The reaction is concentration-dependent. The crystal structures of 1, 2, and 3 have been determined by single-crystal X-ray diffra