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Synthesis and X-ray Analysis of a Sulfur Dioxide Analog of Triamterene

✍ Scribed by de la Cruz, Angeles ;Goya, Pilar ;Páez, Juan Antonio ;Martínez-Ripoll, Martín

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
228 KB
Volume
1994
Category
Article
ISSN
0947-3440

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✦ Synopsis

Abstract

The synthesis and X‐ray analysis of a sulfur dioxide analog of the diuretic agent triamterene, namely 4,7‐diamino‐1‐methyl‐6‐phenylpyrazino[2,3‐c][1,2,6]thiadiazine 2,2‐dioxide (2b), is reported. The compound is devoid of the diuretic properties found in other related pyrazino[2,3‐c][1,2,6]thiadiazines. magnified image

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