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Synthesis and transformations of some pyrido[2,3-d]pyrimidines

✍ Scribed by Marijan Kočevar; Jože Koller; Branko Stanovnik; Miha Tišler


Publisher
Springer Vienna
Year
1987
Tongue
English
Weight
513 KB
Volume
118
Category
Article
ISSN
0026-9247

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Synthesis of pyrido[2,3-d]pyrimidines fr
✍ Francisco Perandones; José L. Soto 📂 Article 📅 1998 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 568 KB

## Abstract 2‐Methoxy‐4‐amino‐5‐pyrimidinecarbaldehyde (2a) as well as its 6‐methyl 2b and 6‐phenyl derivatives 2c were prepared by reduction of the corresponding aminopyrimidinecarbonitriles 1. Catalytic hydrogenation of 1a, 1b gives 5‐hydroxymethylpyrimidines 3a, 3b; under the same conditions 1c