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Pyrido[2,3-d]pyrimidines 4. Synthesis and some transformations of oxo(hydroxy)pyrido[2,3-d]pyrimidines

✍ Scribed by O. A. Burova; N. M. Smirnova; V. I. Pol'shakov; G. S. Chernov; G. A. Losev; T. S. Safonova


Publisher
Springer US
Year
1991
Tongue
English
Weight
587 KB
Volume
27
Category
Article
ISSN
0009-3122

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Synthesis of pyrido[2,3-d]pyrimidines fr
✍ Francisco Perandones; José L. Soto 📂 Article 📅 1998 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 568 KB

## Abstract 2‐Methoxy‐4‐amino‐5‐pyrimidinecarbaldehyde (2a) as well as its 6‐methyl 2b and 6‐phenyl derivatives 2c were prepared by reduction of the corresponding aminopyrimidinecarbonitriles 1. Catalytic hydrogenation of 1a, 1b gives 5‐hydroxymethylpyrimidines 3a, 3b; under the same conditions 1c