Synthesis and study of the rearrangements of 5-(1,2,3-triazol-4-yl)-1,2,3-thiadiazoles

✍ Scribed by Vasiliy A Bakulev; Evgeniy V Tarasov; Yury Yu Morzherin; Ingrid Luyten; Suzanne Toppet; Wim Dehaen

• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 644 KB
• Volume: 54
• Category: Article
• ISSN: 0040-4020
• DOI: 10.1016/s0040-4020(98)00449-9

✦ Synopsis

A method for the synthesis of heterecyclic ring conjugates containing 1,2,3-thiadiazole and 1,2,3-triazole nuclei was elaborated. The mechanism of rearrangement (effect of substituents and solvents) was investigated by NMR spectroscopy. A novel domino-type rearrangement involving both heterocycles was discovered.