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Synthesis and study of sulfonation of 6-methoxy- and 6-hydroxy-2-phenyl-3-hydroxypyridines

โœ Scribed by L. D. Smirnov; M. R. Avezov; V. P. Lezina; R. O. Alieva; K. M. Dyumaev


Book ID
112421816
Publisher
Springer
Year
1971
Tongue
English
Weight
197 KB
Volume
20
Category
Article
ISSN
1573-9171

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A novel Mannich type condensation between the monomethyl ester of acetonedicarboxylic acid, methylamine hydrochloride, and hydrolyzed dimethoxydihydrothran gave 6-or 7-functionalized flketo ester tropanes 12 -15. Further elaboration afforded a series of 6-or 7-hydroxy and 6-or 7methoxy 21~-methoxyca