Notes - Synthesis of 2-Hydroxy(p-methoxy-phenyl)bicyclo[3,3,1]nonane-6,9-dione
β Scribed by Papadakis, Philippos; Hall, Leo; Augustine, Robert
- Book ID
- 126824754
- Publisher
- American Chemical Society
- Year
- 1958
- Tongue
- English
- Weight
- 358 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0022-3263
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The biotransformation of (^)-bicyclo [3.3.1]nonane-2,6-dione by Aspergillus niger and Glomerella cingulata was investigated. The diketone was reduced to the ketoalcohol 2-endo-hydroxy-bicyclo[3.3.1]nonane-6-one and the diol endo,endo-bicyclo[3.3.1]nonane-2,6-diol respectively. Endo,endobicyclo[3.3.1
The title compound has been synthesized stereoselectively based on a new methodology for the construction of erythro-1,3-diols. Endo-1,3-dimethyl-2,9-dioxabicyclo[3.3.1]nonane (11, first isolated by Heemann and Francke in 1976 from Norway spruce attacked by the ambrosia beetle (Tgypodendron Lineatum