## Abstract A route to optically active variously substituted 4‐methyl‐ and 4‐methyl‐7‐substituted 1,3,4,5‐tetrahydro‐2__H__‐1,5‐benzo‐diazepin‐2‐ones as analogues of commercially available Lofendazam (7‐chloro‐5‐phenyl‐1,3,4,5‐tetrahydro‐2__H__‐1,5‐benzodiazepin‐2‐one, 1) was developed. Fortyone v
Synthesis and study of structure of 5-formyl-substituted 2,3,4,5-tetrahydro-1H-1, 5-benzodiazepin-2-ones
✍ Scribed by N. A. Puodzhyunaite; R. A. Yanchene; Z. A. Stumbryavichyute
- Publisher
- Springer US
- Year
- 1988
- Tongue
- English
- Weight
- 401 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0009-3122
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## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract 2a,4‐Disubstituted 5‐benzoyl‐2‐chloro/2,2‐dichloro‐2a,3,4,5‐tetrahydro‐azeto [1,2‐a] [1,5]benzodiazepin‐1 (2H)‐ones (**3a–h**) were synthesized by cycloaddition reactions of 2,4‐disubstituted 1‐benzoyl‐2,3‐dihydr o‐1__H__‐1,5‐benzodiazepines (**2a–h**) and ketenes, generated from chloro
UDC 547.892.07:543. 422.25'51 4-Styryl-2,3-dihydro-iH-l,5-benzodiazepin-2-ones were synthesized and their structure was established by means of PMR spectra and mass spectroscopy. There is no unequivocal information on the structure of the reaction products of 4methyl-2,3-dihydro-iH-l,5-benzodiazepi
An investigation of the molecular dynamics of substituted 1,3,4,5-tetrahydro-2H-l,Ibenzodiazepin-2-0ne derivatives revealed that these molecules adopt cycloheptadiene-like boat conformations. There is an equilibrium between the quasi-axial and the quasiequatorial conformer in which the quasi-axial c