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Synthesis and Structure−Activity Relationships of New 1,3-Disubstituted Cyclohexanes as Structurally Rigid Leukotriene B 4 Receptor Antagonists

✍ Scribed by Poudrel, Jean-Marc; Hullot, Pierre; Vidal, Jean-Pierre; Girard, Jean-Pierre; Rossi, Jean-Claude; Muller, Agnès; Bonne, Claude; Bezuglov, Vladimir; Serkov, Igor; Renard, Pierre; Pfeiffer, Bruno

Book ID
118202562
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
478 KB
Volume
42
Category
Article
ISSN
0022-2623

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ChemInform Abstract: Synthesis and Pharmacological Profile of New 1,3-Disubstituted Cyclohexanes as Leukotriene B4 Receptor Antagonists.
✍ J. M. POUDREL; P. HULLOT; J. P. VIDAL; J. P. GIRARD; J. C. ROSSI; A. MULLER; C. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

Synthesis and Pharmacological Profile of New 1,3-Disubstituted Cyclohexanes as Leukotriene B4 Receptor Antagonists. -Novel non-aromatic members of stable leukotriene B4 antagonists such as (VIII) and (IX) are described, in which the conjugated double bond of the natural eicosanoid (X) is replaced b