𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and Structure−Activity Relationships of 1,2,3,4-Tetrahydroquinoline-2,3,4-trione 3-Oximes: Novel and Highly Potent Antagonists for NMDA Receptor Glycine Site

✍ Scribed by Cai, Sui Xiong; Zhou, Zhang-Lin; Huang, Jin-Cheng; Whittemore, Edward R.; Egbuwoku, Zizi O.; Lü, Yixin; Hawkinson, Jon E.; Woodward, Richard M.; Weber, Eckard; Keana, John F. W.


Book ID
111688931
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
267 KB
Volume
39
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Synthesis and structure–Activity relatio
✍ Zhiqiang Guo; Yongsheng Chen; Dongpei Wu; Yun-Fei Zhu; R.Scott Struthers; John S 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 221 KB

The synthesis and SAR studies of thieno [2,3-d]pyrimidine-2,4-diones as human GnRH receptor antagonists to treat reproductive diseases are discussed. It was found that the 2-(2-pyridyl)ethyl group on the 5-aminomethyl functionality of the core structure was a key feature for good receptor binding ac