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Synthesis and Structure of Symmetrical Bicyclic Hexapeptides Bridged by Metathesis Reaction

✍ Scribed by Giovannoni, Jérôme; Didierjean, Claude; Durand, Philippe; Marraud, Michel; Aubry, André; Renaut, Patrice; Martinez, Jean; Amblard, Muriel


Book ID
127234293
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
86 KB
Volume
6
Category
Article
ISSN
1523-7060

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The Synthesis of Strained Methylene-brid
✍ Konrad B. Becker 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 German ⚖ 800 KB

## Abstract A convenient synthesis of the strained methylene‐bridged __trans__‐cyclooctenes bicyclo[3.3.1]‐1 (2)‐nonene **(1)**, bicyclo[4.2.1]‐1(8)‐nonene **(2)**, and bicyclo[4.2.1]‐1(2)‐nonene **(3)** by the intramolecular __Wittig__ reaction is described (see __Schemes 1–4__). The (3‐oxocycloal