Synthesis and structure-activity relationships of pyrazolo[4,3-d]pyrimidin-7-ones as adenosine receptor antagonists
โ Scribed by Hamilton, Harriet W.; Ortwine, Daniel F.; Worth, Donald F.; Bristol, James A.
- Book ID
- 124092155
- Publisher
- American Chemical Society
- Year
- 1987
- Tongue
- English
- Weight
- 734 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0022-2623
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
1-Methyl-3-propyl-1H-pyrazole-5-carboxylic acid (3) was exclusively brominated at the 4-position by bromine in the dark. Brominated product 8 was then converted into 1-methyl-3-propyl-1H-pyrazole-5-carboxamide 9 by successive treatment with thionyl chloride and ammonium hydroxide. Carboxamide 9 was