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Synthesis and structure-activity relations of fibrinolytic bis(tetrahydroisoquinolines)

✍ Scribed by Fliedner, Leonard J.; Schor, Joseph M.; Myers, Melvyn J.; Pachter, Irwin J.

Book ID
125996795
Publisher
American Chemical Society
Year
1971
Tongue
English
Weight
550 KB
Volume
14
Category
Article
ISSN
0022-2623

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✍ Daniel Berney; Theodor Jauner 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 German ⚖ 372 KB

## Abstract The reaction of 3,4‐dimethoxyphenethylamine with some cyclic aminoketones in the presence of polyphosphoric acid afforded 1‐spiro‐tetrahydroisoquinolines. A two‐step procedure starting from veratrylamine and amino‐ketones gave 3‐spiro‐tetrahydroisoquinolin‐4‐ones. The __Schmidt__ rearra