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Synthesis and Structural Analysis of a β-Hairpin Peptide Containing a Sugar Amino Acid

✍ Scribed by Begoña Aguilera; Gregg Siegal; Herman S. Overkleeft; Nico J. Meeuwenoord; Floris P. J. T. Rutjes; Jan C. M. van Hest; Hans E. Schoemaker; Gijs A. van der Marel; Jacques H. van Boom; Mark Overhand


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
431 KB
Volume
2001
Category
Article
ISSN
1434-193X

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Conformationally constrained amino acid and dipeptide units can serve in mimics of specific secondary structures for studying relationships between peptide conformation and biological activity. A variety of mimics are required to study systematically the structure-activity relationships in biologica