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Synthesis and stereochemistry of N-substituted 3,5-dibenzoyl-4-phenylpiperidines

✍ Scribed by M. V. Denisenko; G. V. Pavel'; M. N. Tilichenko

Book ID
112331409
Publisher
Springer US
Year
1979
Tongue
English
Weight
440 KB
Volume
15
Category
Article
ISSN
0009-3122

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Piperidine derivatives: Synthesis of potential analgesics in 3-substituted 4-phenylpiperidine series
✍ Rana Abbas; Robert E. Willette; J. Michael Edwards 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 421 KB

The syntheses of 1-methyl-3-(3-hydroxy-3-phenylpropyl)-4-phenyl-4-piperidinol and 1-methyl-3(3-hydroxy-3-phenylpropyl)-4-phenyl-4-propanoyloxypiperidine are described. Preliminary pharmacological testing showed these compounds to be weakly active in the writhing test.