✦ LIBER ✦

Piperidine derivatives: Synthesis of potential analgesics in 3-substituted 4-phenylpiperidine series

✍ Scribed by Rana Abbas; Robert E. Willette; J. Michael Edwards

Publisher: John Wiley and Sons
Year: 1977
Tongue: English
Weight: 421 KB
Volume: 66
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.2600661121

No coin nor oath required. For personal study only.

✦ Synopsis

The syntheses of 1-methyl-3-(3-hydroxy-3-phenylpropyl)-4-phenyl-4-piperidinol and 1-methyl-3(3-hydroxy-3-phenylpropyl)-4-phenyl-4-propanoyloxypiperidine are described. Preliminary pharmacological testing showed these compounds to be weakly active in the writhing test.

📜 SIMILAR VOLUMES

ChemInform Abstract: An Efficient Synthe

ChemInform Abstract: An Efficient Synthesis of Some Substituted Piperidin-4-one Thiosemicarbazone Derivatives as Potential Anticonvulsant under Microwave Irradiation.

✍ Sameer Rastogi; Harshita Rastogi 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB

Synthesis, Analgesic and Antiinflammator

Synthesis, Analgesic and Antiinflammatory Properties of Certain 5-/6-Acyl-3-(4-substituted-1-piperazinylmethyl)-2-benzoxazolinones Derivatives.

✍ Meric Koeksal; Nesrin Goekhan; Esra Kuepeli; Erdem Yesilada; Hakki Erdogan 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 22 KB 👁 1 views

Synthesis, Analgesic and Antiinflammator

Synthesis, Analgesic and Antiinflammatory properties of Certain 5-/6-Acyl-3-(4-substituted-1-piperazinylmethyl)-2-benzoxazolinones Derivatives

✍ Meriç Köksal; Nesrin Gökhan; Esra Küpeli; Erdem Yesilada; Hakkı Erdoğan 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 110 KB 👁 2 views

## Abstract The synthesis of a novel series of Mannich bases of 5‐/6‐acyl‐5‐methyl‐2‐benzoxazolinones has been described. The structures attributed to compounds **2a**, **3a**, **4a**, **4b**, **9a**, **9b**, **5a**–**5g**, **6a**–**6g**, **10a**, **10g**, **11a**, **11g** have been elucidated usin

Synthesis and in vitro Antibacterial Act

Synthesis and in vitro Antibacterial Activities of Some 4-Acetylantipyrine-4-substituted-3-thiosemicarbazone Derivatives

✍ Aydin Salman; ÖZnur Ates; Nesrin Cesur; Gülten Ötük 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 154 KB 👁 2 views

ChemInform Abstract: Design, Synthesis a

ChemInform Abstract: Design, Synthesis and Pharmacological Evaluation of a Series of 5-Carbethoxy-4-chloro-6-(substituted amino)pyrimidines as Potential Analgesic and Antiinflammatory Agents with Very Low Ulcerogenic Potential.

✍ Mahesh T. Chhabria; Chamanlal J. Shishoo; Dilip K. Vaghela; Shailesh M. Patel; M 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views

ChemInform Abstract: Synthesis, Spectral

ChemInform Abstract: Synthesis, Spectral, Crystal Structure and in vitro Antimicrobial Evaluation of Imidazole/Benzotriazole Substituted Piperidin-4-one Derivatives.

✍ R. Ramachandran; M. Rani; S. Senthan; Yeon Tae Jeong; S. Kabilan 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 29 KB 👁 2 views