Synthesis and stereochemistry of 3,4-disubstituted sulfolanes
β Scribed by N. N. Novitskaya; B. V. Flekhter; G. A. Tolstikov
- Book ID
- 112335542
- Publisher
- Springer US
- Year
- 1977
- Tongue
- English
- Weight
- 425 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0009-3122
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## Abstract The azabicyclic __endo__ compound 3 was synthesized by reaction of enamine 1 with 2βbenzoylβ1,3βdichloropropane (2). The thermodynamically more stable __exo__ isomer 4 was obtained by epimerization of 3 with sodium methoxide. The reduction of 3 and 4 was carried out with different reduc
The syntheses of four 4-methyl-4-phenyl-l,2,3,4-tetrahydro-Znaphthoic acids are described. The stereospecific cyclization of the cis-isomers and proton NMR studies establishing cistrans product ratios are also reported. Keyphrases 0 Tetralins, substituted-synthesis, stereochemistry of 4,4-disubstit