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Synthesis and spectroscopic characterizations of both 1-ethyl-4,8-dihydro-10-methoxy-3-methyl-8-r1-6-r2-dipyrazolo[3,4-b:4′,3′-f]-[1,5]diazocin-5(1H)-ones and 1-ethyl-1,4,8,9-tetrahydro-3,9-dimethyl-8-r1-6-r2-dipyrazolo[3,4-b:4′,3′-f][1,5]diazocine-5,10-diones of pharmaceutical interest

✍ Scribed by Onofrio Migliara; Liliana Lamartina; Rosina Rainieri


Book ID
112131371
Publisher
Journal of Heterocyclic Chemistry
Year
1995
Tongue
English
Weight
337 KB
Volume
32
Category
Article
ISSN
0022-152X

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2,8-Dimethoxy-4,10-dimethyl-1,3,7,9-tetr
✍ Bhuiyan, M. Delower H. ;Jensen, Paul ;Try, Andrew C. 📂 Article 📅 2007 🏛 International Union of Crystallography 🌐 English ⚖ 488 KB

In the molecule of the title compound, C~19~H~18~N~6~O~10~, the 2,8-dimethoxy-4,10-dimethyl-1,3,7,9-tetranitro analogue of Tröger's base, the diazocine bridge imparts a twist such that the two aryl rings are offset with respect to one another. The hinge angle of the molecule, measured as the dihedra